FIG 1.

Growth curves of wild-type and mutant CDC-9 in human intestinal epithelial cells (Caco-2). Caco-2 cells were infected with CDC-9 P11, P28, or P44 or RRV at an MOI of 0.1 or mock treated in the same manner. At the indicated time points, infected cultures were collected, and titration was performed in MA104 cells. The data are means and 3 standard errors from 3 independent experiments in triplicate (n = 9). Statistical analysis was performed to compare titers of CDC-9 P11 with those of CDC-9 P28, P44, or RRV by using a paired t test. Titers from CDC-9 P28- and P44-infected cultures were similar. ns, not significant (P > 0.05); *, P ≤ 0.05; **, P < 0.01.