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Treatment effects of CPFX and TETRA on cellular metabolism (figure 1A, B), ROS levels (figure 1C, D) and mitochondrial membrane potential (MMP, figure 1E, F) in ARPE-19 cells after 24, 48 and 72 hours as measured with the MTT, H2DCFDA and JC-1 assays. *P<0.05, **P<0.01. ARPE-19, human retinal pigment epithelial cells; CPFX, ciprofloxacin; H2DCFDA, 2’,7’-dichlorodihydrofluorescein diacetate; ns, not significant; ROS, reactive oxygen species; TETRA, tetracycline.
