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. 2020 Jul 21;5(1):e000458. doi: 10.1136/bmjophth-2020-000458

Figure 4.

Figure 4

Expression of inflammatory pathway genes (A) IL-6, (B) IL-1β, (C) IL-33, (D) TGF-α1, (E) TGF-β1 and (F) TGF-β2 in CPFX and TETRA treated ARPE19 cells. *P<0.05, **P<0.01, ***P<0.001. ARPE19, human retinal pigment epithelial cells; Cont, untreated control; CPFX, ciprofloxacin; HCl, hydrochloric acid vehicle control; IL-6, interleukin-6; Meth, methanol vehicle control; ns, not significant; TETRA, tetracycline; TGF-β1, transforming growth factor-β1.