Table 3.

Summary of computed kinetic image features in five groups.^a These features are computed from three different regions—background parenchymal region of the whole (left and right) breast regions, left breast and right breast.^b Absolute bilateral feature difference of BPE between the left and right breasts. Reprinted with permission from: Aghaei F, Tan M, Hollingsworth AB, Qian W, Liu H, Zheng B. Computer-aided breast MR image feature analysis for prediction of tumor response to chemotherapy. Med Phys. 2015; 42(11):6520-8.

Feature group	Feature number	Description
Tumor area	1–7	Volume, average intensity, maximum pixel intensity, standard deviation, and skewness of tumor pixel intensity, maximum value of tumor radius, and shape factor
Enhanced area	8–11	Volume, average intensity, standard deviation, and skewness of contrast-enhanced pixel intensity
Necrotic area	12–16	Volume, average intensity, standard deviation, and skewness of low-enhanced pixel intensity, ratio of necrotic volume over tumor volume
Background parenchymal areaa	17–34	Average intensity, standard deviation, skewness, maximum pixel intensity, average value of top 1%, and average value of top 5% of pixel values
Absolute bilateral difference of BP areab	35–39	Average intensity, standard deviation, skewness, average value of top 1%, and average value of top 5% of pixel values