Table 1.
First-line | Second-line | Third-line | Abbreviation | |
---|---|---|---|---|
Sequence 1 | Pertuzumab + trastuzumab + docetaxel (THP) [17] | T-DM110 | Capecitabine + lapatinib [7] | THP → TDM1 → Cape/Lapat |
Sequence 2 | Pertuzumab + trastuzumab + docetaxel (THP) [17] | Trastuzumab + lapatiniba16 | Trastuzumab + capecitabine [18] | THP → Trastuz/Lapat → Trastuz/Cape |
Sequence 3 | Trastuzumab plus docetaxel [17] | T-DM110 | Trastuzumab + lapatiniba16 | Trastuz/Docet → T-DM1 → Trastuz/Lapat |
Sequence 4 | Trastuzumab plus docetaxel [17] | Trastuzumab + lapatiniba16 | Trastuzumab + capecitabine [18] | Trastuz/Docet →Trastuz/Lapat → Trastuz/Cape |
Rarely used in the Taiwanese setting; Abbreviation: T-DM1, ado-trastuzumab emtansine.