Fig 3. Relation of CSF HIV-1 RNA and CSF:plasma HIV- RNA ratio to CSF WBC counts.

A. Linear regressions plotting the relation of the log₁₀ CSF HIV-1 RNA concentrations per mL to the log₁₀ CSF WBC counts per μL in the treated (lower line) and untreated (upper line) subjects. Symbol colors are as in Fig 1 as per legend. The larger symbols for the no escape subjects indicate two points with overlapping values. B. Linear regression plotting the relation of the CSF:plasma HIV-1 RNA ratio (calculated as log₁₀ difference between CSF and plasma HIV-1 RNA values) to the log₁₀ CSF WBC counts per μL. The horizontal dotted line indicates equivalent values in CSF and plasma. Open symbols are the same colors as in Fig 1. Statistics shown are the P and R squared values from the linear regressions which are plotted with 95% confidence intervals.