Table 1. People living with HIV and herpes zoster co-infection.
Code | LP days after zoster debut | Zoster location | HIV treatment | CD4 cells/ml | HIV copies/ml | CSF-mono cells x 106/l | ||
---|---|---|---|---|---|---|---|---|
Plasma | CSF | |||||||
On ART secondary CSF escape | ||||||||
35037 | 11 | Th4-5 | ABC, 3TC DRV/r | 470 | <20 | 757 | 301 | |
5348 | 30 | Th2-3 | TDF, FTC ATV/r | 300 | <50 | 1920 | 67 | |
5240 | 150 | Thorax | DRV/r, ABC | 790 | <50 | 478 | 17 | |
50156 | 12 | Thorax | TDF, EFV FTC | 320 | 54 | 76 | 19 | |
On ART no CSF escape | ||||||||
5529 | 39 | Facial | ZDV, 3TC ATV/r | 320 | <20 | <20 | <3 | |
5294 | 6 | Thorax | ABC, 3TC DTG | 540 | <20 | <20 | 14 | |
5216 | 2 | Facial | ABC, 3TC DTG | 450 | <20 | <20 | 18 | |
38069 | 4 | Thorax | TDF, FTC EFV | 340 | <20 | <20 | <3 | |
15399 | 13 | Thorax | ABC, 3TC DTG | 470 | <20 | <20 | 14 | |
Off ART CSF discordance | ||||||||
1 | 18 | Th2-4 | 0 | 713 | 55300 | 322000 | 245 | |
2 | 22 | Facial | 0 | 330 | 105000 | 148000 | 9 | |
3 | 28 | L4-S1 | 0 | 240 | 141000 | 366000 | 30 | |
4 | 16 | Arm | 0 | 400 | 32793 | 1000000 | 49 | |
5 | 28 | Thorax | 0 | 240 | 77613 | 296850 | 41 | |
6 | 11 | L2-L3 | 0 | 170 | 18511 | 88213 | 26 | |
7 | 60 | Thorax | 0 | 370 | 49912 | 63775 | 24 | |
8 | <1 | Thorax | 0 | 490 | 17000 | 66000 | 59 | |
Off ART no CSF discordance | ||||||||
9 | 6 | Th2-4 | 0 | 400 | 260000 | 179000 | 32 | |
10 | 97 | Arm | 0 | 170 | 258000 | 32000 | 2 | |
11 | 50 | C5 | 0 | 330 | 302000 | 98800 | 7 | |
12 | 1 | Thorax | 0 | 250 | 66700 | 7650 | 6 | |
13 | 91 | Ophtalmicus | 0 | 170 | 686275 | 40167 | 2 | |
14 | 60 | Thorax | 0 | 169 | 22248 | 3144 | 1 | |
15 | 1 | Th10-11 | 0 | 10 | 97396 | 125 | 0 | |
16 | 35 | Oticus | 0 | 148 | 69400 | 542 | 0 | |
Secondary escape/other co-infections | ||||||||
M 62 y | Neuroborreliosis | ABC, 3TC EFV | 320 | <20 | 219 | 94 | ||
5138 | HSV-2 encephalitis | DRV/r, RTG | 130 | <50 | 1012 | 211 |
ABC = abacavir, 3TC = lamivudine, DRV = darunavir, r = booster ritonavir, ATV = atazanavir, EFV = efavirenz, RTG = raltegravir
TDF = tenofovir, ETR = etravirine, FTC = Emtricitabine. HSV enc = Herpes simplex virus encephalitis. LP = lumbar puncture.
ART = antiretroviral treatment, CSF escape = Increased HIV count in cerebrospinal fluid (CSF) while effective HIV treatment in plasma.