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. 2020 Jul 22;15(7):e0236162. doi: 10.1371/journal.pone.0236162

Table 1. People living with HIV and herpes zoster co-infection.

Code LP days after zoster debut Zoster location HIV treatment CD4 cells/ml HIV copies/ml CSF-mono cells x 106/l
Plasma CSF
On ART secondary CSF escape
35037 11 Th4-5 ABC, 3TC DRV/r 470 <20 757 301
5348 30 Th2-3 TDF, FTC ATV/r 300 <50 1920 67
5240 150 Thorax DRV/r, ABC 790 <50 478 17
50156 12 Thorax TDF, EFV FTC 320 54 76 19
On ART no CSF escape
5529 39 Facial ZDV, 3TC ATV/r 320 <20 <20 <3
5294 6 Thorax ABC, 3TC DTG 540 <20 <20 14
5216 2 Facial ABC, 3TC DTG 450 <20 <20 18
38069 4 Thorax TDF, FTC EFV 340 <20 <20 <3
15399 13 Thorax ABC, 3TC DTG 470 <20 <20 14
Off ART CSF discordance
1 18 Th2-4 0 713 55300 322000 245
2 22 Facial 0 330 105000 148000 9
3 28 L4-S1 0 240 141000 366000 30
4 16 Arm 0 400 32793 1000000 49
5 28 Thorax 0 240 77613 296850 41
6 11 L2-L3 0 170 18511 88213 26
7 60 Thorax 0 370 49912 63775 24
8 <1 Thorax 0 490 17000 66000 59
Off ART no CSF discordance
9 6 Th2-4 0 400 260000 179000 32
10 97 Arm 0 170 258000 32000 2
11 50 C5 0 330 302000 98800 7
12 1 Thorax 0 250 66700 7650 6
13 91 Ophtalmicus 0 170 686275 40167 2
14 60 Thorax 0 169 22248 3144 1
15 1 Th10-11 0 10 97396 125 0
16 35 Oticus 0 148 69400 542 0
Secondary escape/other co-infections
M 62 y Neuroborreliosis ABC, 3TC EFV 320 <20 219 94
5138 HSV-2 encephalitis DRV/r, RTG 130 <50 1012 211

ABC = abacavir, 3TC = lamivudine, DRV = darunavir, r = booster ritonavir, ATV = atazanavir, EFV = efavirenz, RTG = raltegravir

TDF = tenofovir, ETR = etravirine, FTC = Emtricitabine. HSV enc = Herpes simplex virus encephalitis. LP = lumbar puncture.

ART = antiretroviral treatment, CSF escape = Increased HIV count in cerebrospinal fluid (CSF) while effective HIV treatment in plasma.