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Diagnostic accuracy of raised CA 15–3 and CEA tumour marker velocity for cancer recurrence.
| AUROC (95% CI) | Sensitivity (%) | Specificity (%) | NPV (%) | PPV (%) | |
|---|---|---|---|---|---|
| CA 15–3 velocity >2.5 U/mL/year |
0.85 (0.78, 0.91) | 88.1 | 82.1 | 87.3 | 83.1 |
| CEA velocity >1.2ng/mL/year | 0.79 (0.71, 0.88) | 73.8 | 85.1 | 78.1 | 81.8 |
| Either CA 15–3 or CEA tumour marker velocity above threshold values | 0.84 (0.76, 0.91) | 94.0 | 73.1 | 92.5 | 77.8 |
