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. 2020 May 20;52:95–101. doi: 10.1016/j.breast.2020.05.005

Table 5.

Association between CA 15–3 velocity, CEA velocity, either CA 15–3 or CEA velocity and cancer recurrence after adjusting for tumour clinicopathological characteristics.

Recurrence
Unadjusted
Adjusted
No (%) Yes (%) OR (95% CI) p-value OR (95% CI) p-value
CA 15–3 velocity
<=2.5U/mL/year 55 (87.3) 8 (12.7) REF P<0.001
>2.5U/mL/year 12 (16.9) 59 (83.1) 33.8 (12.9, 88.9)
CEA velocity
<=1.2ng/mL/year 57 (78.1) 16 (21.9) REF P<0.001
>1.2ng/mL/year 10 (18.2) 45 (81.8) 16.0 (6.6, 38.7)
Combined criteria either CA 15–3 or CEA velocity
CA 15–3 ≤ 2.5 & CEA ≤ 1.2 49 (92.5) 4 (7.5) REF P < 0.001 REF P < 0.001
CA 15–3 >2.5 or CEA >1.2 18 (22.2) 63 (77.8) 42.9 (13.6, 134.9) 73.4 (12.0, 448.6)