Table 4.
Multivariate prognostic analyses by 21-gene RS stratifications.
| Variables | Low-risk |
Intermediate-risk |
High-risk |
|||
|---|---|---|---|---|---|---|
| HR (95%CI) | P | HR (95%CI) | P | HR (95%CI) | P | |
| Traditional RS cutoffs | ||||||
| No chemotherapy | 1 | 1 | 1 | |||
| Chemotherapy | 2.155 (0.324–14.326) | 0.427 | 0.877 (0.297–2.592) | 0.812 | 0.337 (0.113–1.003) | 0.051 |
| TAILORx RS cutoffs | ||||||
| No chemotherapy | – | 1 | ||||
| Chemotherapy | – | – | 1.907 (0.641–5.673) | 0.246 | 0.368 (0.151–0.897) | 0.025 |
Abbreviations: CI, confidence interval; HR, hazard ratio; RS, recurrence score; TAILORx, Trial Assigning Individualized Options for Treatment.