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. Author manuscript; available in PMC: 2020 Dec 25.
Published in final edited form as: N Engl J Med. 2020 Jun 25;382(26):2493–2503. doi: 10.1056/NEJMoa1916624

Figure 1. Serum Urate and Iohexol-based Glomerular Filtration Rate (GFR) Trajectories.

Figure 1.

The mean levels of serum urate (Panel A) and the mean iohexol-based GFR (Panel B) in the two groups are shown at different time points during the trial. I bars indicate 95% confidence intervals. The mean serum urate values are shown for participants with available levels at each time point. The mean iohexol-based GFR values are shown for the entire intention-to-treat population, with missing values imputed as described in the Methods section. The intervention period ended at week 156 after randomization, and the 2-month washout period ended at week 164. To convert the values for serum urate to micromoles per liter, multiply by 59.48.