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ΔfakA mutant causes altered cytokine expression in the host. Mice were subcutaneously infected with 1 × 107 to 3 × 107 CFU of WT or ΔfakA mutant S. aureus. Mice were sacrificed 4 or 7 days p.i. Infection site skin was collected and cytokine levels measured in homogenate. Dots indicate an individual mouse (n = 6), whereas bars indicate the median. *, P < 0.05; **, P < 0.01 by Mann-Whitney test. KC, keratinocyte chemoattractant. MIP, macrophage inflammatory protein.
