Appendix 1—figure 15. Status Epilepticus patient 1.

(A) Initiation (left) of seizure that begins to terminate with a SH/SNIC bifurcation, then transitions into a SupH onset. The post-seizure baseline (right) returns to prior levels. The seizure lasted >24 hr, but due to signal dropout the exact time of termination was not recorded. Inset a2: expanded view of indicated portion of seizure start. (B) Subclinical status epilepticus was characterized by irregular firing interspersed with periods of organized, lower amplitude EEG. (C, D) Expanded view of (c1, d1) from B, with further expansion of (c2, d2). The irregular firing organizes several times into discrete seizures that nearly terminate with SH dynamics, but revert to the previous pattern. (E) Later in the seizure, there is waxing/waning of the firing pattern, similar to Figure 5D–F.