Table 2. Histological and morphological findings described by the renal biopsy.
Histological abnormalities | |
---|---|
Gross | LM: single fragmented core measured ∼0.8 cm EM: single core measured 0.8 cm |
Light microscopy |
Sections examined revealed corticomedullary renal tissue core containing
10
glomeruli.
• 7/10 glomeruli are globally sclerosed with periglomerular fibrosis • 3/10 of glomeruli show segmental sclerosis • Marked tubular atrophy is seen together with intraluminal hyaline casts; some tubules are dilated • Severe mixed tubulointerstitial inflammation and fibrosis were found • Thick-walled blood vessels are noted |
Immunostaining | • lgG, lgM, lgA: focal mesangial (1+) |
Abbreviations: EM, electron microscopy; Ig, immunoglobulin; LM, light microscopy.