Table 1. Lifespan and climbing gene candidates identified by genome-wide association.

Effect size data shown in Data S4. See also Figure S3A-D.

Phenotype	Gene	Marker	Effect/ Location	p value	FDR	Type	Description
75% Survival		3L:12,638,741		2.50E-05	0%
	CR32111	3L:12,638,748	3’ UTR	4.16E-05	3%	Interaction	nc transcript
		3L:12,638,743		4.50E-05	3%
	CG43203	3R:15,179,932	ns	3.39E-05	3%	Interaction	Unknown function
	CG34351	2L:4,707,945	Intron	8.34E-05	8%	Interaction	Neuronal G-protein regulator
	CG8312	3R:5,443,281	Intron	1.04E-04	10%	Interaction	PHD protein
Median LS	CG5888	2L:16,447,864	Intron	4.67E-10	10%	Genotype	Leucine-rich repeat protein
	CG5888	2L:16,447,727	Intron	2.02E-10	0%	Interaction	Leucine-rich repeat protein
		3L:12,638,741		4.81E-05	0%
	CR32111	3L:12,638,748	3’ UTR	5.80E-05	0%	Interaction	nc transcript
		3L:12,638,743		8.13E-05	3%
	CG31221	3R:15,265,527	Intron	7.62E-05	3%	Interaction	Low-density lipoprotein receptor
	CR45580	3R:722,994	nc region	1.44E-04	10%	Interaction	nc transcript
50% climbing decline	CR43930	3L:20,907,785	Upstream	1.50E-04	0%	Interaction	Unknown function
Day below 20% climbing	CG33690	3L:16,195,836	Downstream	3.42E-05	3%	Interaction	Unknown function
		3L:16,195,839		3.54E-05	3%
		3L:16,195,821		4.36E-05	3%
		3L:16,195,833		5.07E-05	3%
		3L:16,195,854		5.97E-05	4%
		3L:16,195,865		1.43E-04	5%
		3L:16,195,864		1.81E-04	9%

LS = lifespan; ns = non-synonymous; nc = non-coding; genotype, interaction, and case control terms detailed in Methods