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. 2020 Jan 21;20(4):586–594. doi: 10.1038/s41397-020-0147-4

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© The Author(s), under exclusive licence to Springer Nature Limited 2020

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Fig. 3 — a Genotypes CYP2A6/6 and CYP2A6/7 of the CYP2A6 gene vs percentage of 3HC analyte in the Total-Nic-Eq. b GG and GT genotypes of the rs145014075 variant of CYP2A6 vs creatinine-adjusted levels of nicotine. c TT and TC genotypes of the variant rs12471326 of the UGT1A9 gene vs percentage of cotinine-Gluc analyte in the Total-Nic-Eq. A Mann–Whitney test for STATA (College station, TX) was used to make the comparisons of the genotypes and the levels of the metabolites. Metabolite levels are shown as percentage of analyte in the Total-Nic-Eq and creatinine-adjusted levels and are shown as the mean ± standard error.