Table 2. GO terms for 17 genes that were commonly upregulated in nano-scaffold groups.
| Gene abbreviation | Gene full name | GO: Biological Process | GO term | |
|---|---|---|---|---|
| A-type and B-type (A>B) | ESRG | Embryonic stem cell-related gene protein | ND | NA |
| CYP26C1 | Cytochrome P450 26C1 | Central nervous system development; anterior/posterior pattern specification; neural crest cell development | GO: 0007417 | |
| GO:0009952 | ||||
| GO:0014032 | ||||
| TFAP2A | Transcription factor AP-2alpha | Trigeminal nerve development; retina layer development | GO:0021559 | |
| GO:0010842 | ||||
| BMPER | BMP-binding endothelial regulator protein | Negative regulation of BMP signaling pathway; positive regulation of ERK1 and ERK2 cascade | GO:0030514 | |
| GO:0070374 | ||||
| PAX3 | Paired box protein-3 | Animal organ morphogenesis; nervous system development | GO:0009887 | |
| GO:0007399 | ||||
| OLIG3 | Oligodendrocyte transcription factor 3 | Spinal cord motor neuron differentiation; regulation of gene expression | GO:0021520 | |
| GO:0000122 | ||||
| POU5F1 | POU domain, class 5, transcription factor 1 | Anatomical structure morphogenesis; blastocyst development | GO:0009653 | |
| GO:0001824 | ||||
| TFAP2B | Transcription factor AP-2beta | Regulation of cell differentiation; regulation of BMP signaling pathway | GO:0045595 | |
| GO:0030510 | ||||
| A-type and B-type (A<B) | KLHL4 | Kelch-like protein 4 | Actin binding | GO:0003779 |
| GBX2 | Homeobox protein GBX-2 | Nervous system development; hindbrain development; forebrain neuron development | GO:0007399 | |
| GO:0030902 | ||||
| GO:0021884 | ||||
| ITPR2 | Inositol 1,4,5-trisphosphate receptor type 2 | Calcium ion transport; cellular response to cAMP | GO:0071320 | |
| GO:0071320 | ||||
| CNTNAP3B | Contactin-associated protein-like 3B | Cell adhesion | GO:0007155 | |
| FOXC1 | Forkhead box protein C1 | Anatomical structure morphogensis; chemokine-mediated signaling pathway; eye development | GO:0009653 | |
| GO:0070098 | ||||
| GO:0001654 | ||||
| PAX8 | Paired box protein-8 | Anatomical structure morphogenesis; central nervous system development; | GO:0009653 | |
| GO:0007417 | ||||
| NTS | Neurotensin/neuromedin N | G protein-coupled receptor signaling pathway; | GO:0007186 | |
| ADGRL4 | Adhesion G protein-coupled receptor L4 | Cell surface receptor signaling pathway; adenylate cyclase-activating G protein-coupled receptor signaling pathway | GO:0007166 | |
| GO:0007189 | ||||
| CHGA | Chromogranin-A | Negative regulation of neuron death; protein localization to secretory granule | GO:1901215 | |
| GO:0003366 |
ND, not determined; NA, not applicable; BMP, bone morphogenetic protein.