Table 5.

Details of patients who died due to retinoblastoma

Case	Age group	High-risk retinoblastoma	Details of high-risk features	Adjuvant chemotherapy	Adjuvant radiotherapy
1	<1 year	Yes	Massive choroidal invasion	Yes	No
2a	<1 year	No	N/A	N/A	N/A
3	<1 year	Yes	Anterior chamber seeding; ciliary body infiltration; massive choroidal invasion; involvement of optic nerve transection; scleral infiltration; extrascleral infiltration	Yes	No
4	1–2 years	Yes	Massive choroidal invasion; involvement of optic nerve transection; scleral infiltration; extrascleral infiltration	Yes	Yes
5	1–2 years	Yes	Massive choroidal invasion; post-laminar optic nerve infiltration; scleral infiltration;	Yes	No
6	1–2 years	Yes	Massive choroidal invasion	Yes	No
7	1–2 years	Yes	Massive choroidal invasion; post-laminar optic nerve infiltration	Yes	No
8	2–3 years	Yes	Massive choroidal invasion; post-laminar optic nerve infiltration; scleral infiltration; extrascleral infiltration	Yes	No
9	2–3 years	Yes	Massive choroidal invasion; post-laminar optic nerve infiltration; scleral infiltration; extrascleral infiltration	Yes	No
10	2–3 years	Yes	Massive choroidal invasion; involvement of optic nerve transection; scleral infiltration	Yes	No
11	2–3 years	Yes	Massive choroidal invasion; involvement of optic nerve transection; scleral infiltration; extrascleral infiltration	Yes	Yes
12	2–3 years	Yes	Anterior chamber seeding; iris infiltration; ciliary body infiltration; massive choroidal invasion; involvement of optic nerve transection; scleral infiltration; extrascleral infiltration	Yes	Yes
13	2–3 years	Yes	Massive choroidal invasion; involvement of optic nerve transection	Yes	Yes
14	3–4 years	Yes	Post-laminar optic nerve infiltration	Yes	No
15	3–4 years	Yes	Anterior chamber seeding; ciliary body infiltration; massive choroidal invasion; involvement of optic nerve transection; scleral infiltration	Yes	No
16	3–4 years	Yes	Anterior chamber seeding; iris infiltration; ciliary body infiltration; massive choroidal invasion; post-laminar optic nerve infiltration	Yes	No
17	3–4 years	Yes	Iris infiltration; ciliary body infiltration; massive choroidal invasion; post-laminar optic nerve infiltration	Yes	No
18	>4 years	Yes	Involvement of optic nerve transection	Yes	Yes
19	>4 years	Yes	Massive choroidal invasion; post-laminar optic nerve infiltration	Yes	No
20	>4 years	Yes	Involvement of optic nerve transection	Yes	Yes
21	>4 years	Yes	Post-laminar optic nerve infiltration	No	No
22	>4 years	Yes	Massive choroidal invasion; involvement of optic nerve transection	Yes	Yes

N/A not applicable

^aOne patient died due to non-compliance to treatment for the contralateral eye, which progressed to develop extraocular tumour extension. There were no high-risk features in the enucleated eye