Table 4.

Prognostic performance of risk assessment strategies with regard to in-hospital all-cause mortality

	OR (95% CI), p value	AUC (95% CI)	Sensitivity (95% CI)	Specificity (95% CI)	PPV (95% CI)	NPV (95% CI)	Negative LR (95% CI)	Positive LR (95% CI)
Modified FAST score	2.2 (1.1–4.5) p = 0.030	0.65 (0.57–0.72)	0.53 (0.46–0.69)	0.66 (0.63–0.69)	0.06 (0.04–0.09)	0.97 (0.96–0.98)	1.6 (1.1–2.2)	0.7 (0.5–1.0)
Bova score*	1.3 (0.6–2.9) p = 0.569	0.62 (0.53–0.70)	0.25 (0.13–0.42)	0.79 (0.76–0.82)	0.04 (0.02–0.08)	0.97 (0.95–0.98)	1.2 (0.7–2.2)	0.9 (0.8–1.16)
2019 ESC algorithm*	5.8 (2.8–12.0) p < 0.001	0.73 (0.64–0.81)	0.59 (0.42–0.74)	0.80 (0.77–0.82)	0.10 (0.07–0.15)	0.98 (0.97–0.99)	3.0 (2.2–4.1)	0.5 (0.3–0.8)

^**The three-level 2019 ESC algorithm and Bova score were dichotomized as low- and intermediate-low risk (low risk) versus intermediate-high risk (intermediate-high risk)

ESC European Society of Cardiology, FAST H-FABP, syncope, tachycardia, H-FABP heart-type fatty acid-binding protein, OR odds ratio, AUC area under the curve, CI confidence interval, PPV positive predictive value, NPV negative predictive value, LR likelihood ratio