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. 2020 Apr 21;27(8):2174–2184. doi: 10.1016/j.sjbs.2020.04.024

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© 2020 The Author(s)

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

PMC Copyright notice

Fig. 2 — Apocynin activates NOX during tIRI. Bar Graphs representing the concentrations of (A) NADP⁺, (B) NADPH and (C) their ratio. While NADP displayed a significant increase in NADP⁺ concentration during tIRI, NADPH levels were reduced as compared to sham and apocynin-treated groups. This resulted in a significant increase in the NADP⁺/NADPH ratio during tIRI indirectly suggesting NOX activation during tIRI. No significant difference was obtained between contralateral testes (P < 0.05). Data are presented as mean ± SD (n = 6/group). *tIRI compared to sham and ^#apocynin compared to tIRI. I = Ipsilateral and C = Contralateral.