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. 2020 Jul 22;10:12221. doi: 10.1038/s41598-020-69199-1

Table 3.

Abnormal results of the dRVVT test depending on anticoagulant treatment.

Anticoagulant Proportion of patients with abnormalities in the dRVVT, n
Controls aPLneg aPLlow aPLhigh
None or discontinued 2% (34) 4% (36) 8% (14) 32% (23)
Rivaroxaban 66% (301)* 79% (73)* 84% (31)*
Apixaban 7% (7) 12% (3) 33% (5)
VKA 19% (107)* 27% (32)* 64% (54)*
LMWH 6% (14) 17% (10) 38% (13)

Patients with a prolonged dRVVT screen and a dRVVT ratio > 1.2 were considered abnormal.

dRVVT, dilute Russell viper venom time; LMWH, low molecular weight heparin; NS, not significant; VKA, vitamin K antagonist.

*Significantly higher in comparison to the cohort with no or discontinued anticoagulants (P < 10–4 for all significantly different comparisons, calculated using the chi-squared test).