Table 3.
Abnormal results of the dRVVT test depending on anticoagulant treatment.
Anticoagulant | Proportion of patients with abnormalities in the dRVVT, n | |||
---|---|---|---|---|
Controls | aPLneg | aPLlow | aPLhigh | |
None or discontinued | 2% (34) | 4% (36) | 8% (14) | 32% (23) |
Rivaroxaban | – | 66% (301)* | 79% (73)* | 84% (31)* |
Apixaban | – | 7% (7) | 12% (3) | 33% (5) |
VKA | – | 19% (107)* | 27% (32)* | 64% (54)* |
LMWH | – | 6% (14) | 17% (10) | 38% (13) |
Patients with a prolonged dRVVT screen and a dRVVT ratio > 1.2 were considered abnormal.
dRVVT, dilute Russell viper venom time; LMWH, low molecular weight heparin; NS, not significant; VKA, vitamin K antagonist.
*Significantly higher in comparison to the cohort with no or discontinued anticoagulants (P < 10–4 for all significantly different comparisons, calculated using the chi-squared test).