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. 2020 Jul 22;10:12221. doi: 10.1038/s41598-020-69199-1

Table 4.

Abnormal results of LA-sensitive aPTT depending on anticoagulant treatment.

Anticoagulant Proportion of patients with abnormalities in the LA-sensitive aPTT, n
Controls aPLneg aPLlow aPLhigh
None or discontinued 3% (47) 2% (19) 5% (9) 15% (11)
Rivaroxaban 2% (9) 5% (5) 54% (20)*
Apixaban 7% (7) 0% (0) 20% (3)
VKA 3% (15) 11% (13) 26% (22)
LMWH 5% (12) 16% (9) 32% (11)

Patients with a prolonged LA-sensitive aPTT and a ratio of LA-sensitive aPTT/aPTT > 1.2 were considered abnormal.

LMWH, low molecular weight heparin; VKA, vitamin K antagonist.

*Significantly higher in comparison to the cohort with no or discontinued anticoagulants (P < 10–4), calculated using the chi-squared test.