Table 4.
Anticoagulant | Proportion of patients with abnormalities in the LA-sensitive aPTT, n | |||
---|---|---|---|---|
Controls | aPLneg | aPLlow | aPLhigh | |
None or discontinued | 3% (47) | 2% (19) | 5% (9) | 15% (11) |
Rivaroxaban | – | 2% (9) | 5% (5) | 54% (20)* |
Apixaban | – | 7% (7) | 0% (0) | 20% (3) |
VKA | – | 3% (15) | 11% (13) | 26% (22) |
LMWH | – | 5% (12) | 16% (9) | 32% (11) |
Patients with a prolonged LA-sensitive aPTT and a ratio of LA-sensitive aPTT/aPTT > 1.2 were considered abnormal.
LMWH, low molecular weight heparin; VKA, vitamin K antagonist.
*Significantly higher in comparison to the cohort with no or discontinued anticoagulants (P < 10–4), calculated using the chi-squared test.