Table 3.
Association of ERG parameters and clinical visual function & prognosis variables in eyes with CRAO.
| Parameters | Initial BCVA | Initial VFDs | Visual acuity improvement (N = 110) | P†‡ | Visual field improvement (N = 54)¶ | P†‡ | |||
|---|---|---|---|---|---|---|---|---|---|
| P* | P†‡ | BCVA improvement (N = 50) | No improvement (N = 60) | Visual field improvement (N = 25) | No improvement (N = 29) | ||||
| Standard treatment : Intra-arterial thrombolysis | 17 : 33 | 19 : 41 | .795# | 7 : 18 | 7 : 22 | .805# | |||
| Dark-adapted 0.01 | B-wave amplitude (μV) | .636 | .274† | 131.45 ± 91.55 | 109.57 ± 92.13 | .174† | 180.81 ± 96.84 | 139.92 ± 92.96 | .120† |
| Implicit time (ms) | .597 | .661† | 91.41 ± 17.36 | 97.52 ± 18.70 | .055† | 87.50 ± 16.47 | 85.34 ± 15.37 | .620† | |
| Dark-adapted 3.0 | A-wave amplitude | .941 | .773† | 163.51 ± 61.19 | 149.79 ± 67.58 | .227† | 185.79 ± 73.36 | 170.84 ± 67.30 | .438† |
| A-wave implicit time | .676 | .593† | 24.41 ± 1.98 | 24.88 ± 3.35 | .310† | 24.03 ± 2.67 | 25.07 ± 2.83 | .172† | |
| B-wave amplitude | .339 | .093† | 333.98 ± 67.81 | 217.19 ± 73.85 | .004† | 342.92 ± 56.48 | 245.74 ± 65.30 | .006† | |
| B-wave implicit time | .843 | .779† | 50.33 ± 5.55 | 51.19 ± 7.47 | .460† | 50.28 ± 5.58 | 50.62 ± 7.44 | .850† | |
| B/A ratio | < .001 | < .001‡ | 1.68 ± 0.31 | 1.43 ± 0.21 | .023‡ | 1.83 ± 0.23 | 1.46 ± 0.19 | .008‡ | |
|
Dark-adapted 3.0 Oscillatory potentials |
.691 | .641‡ | 35.34 ± 21.53 | 30.01 ± 21.20 | .154‡ | 44.43 ± 23.77 | 40.67 ± 21.45 | .544‡ | |
|
Light-adapted 3.0 |
A-wave amplitude | .250 | .289† | 21.99 ± 11.91 | 19.33 ± 8.99 | .156† | 10.79 ± 2.15 | 11.43 ± 2.12 | .107† |
| A-wave implicit time | .812 | .952† | 16.41 ± 2.48 | 16.56 ± 3.43 | .767† | 15.71 ± 2.20 | 14.93 ± 2.60 | .244† | |
| B-wave amplitude | .344 | .087† | 69.34 ± 34.52 | 63.28 ± 38.41 | .330† | 83.84 ± 37.68 | 63.96 ± 36.84 | .037† | |
| B-wave implicit time | .597 | .084† | 32.71 ± 2.92 | 34.17 ± 3.19 | .007† | 32.42 ± 2.28 | 33.70 ± 3.16 | .090† | |
| Photopic negative response | .071 | .375† | − 22.14 ± 4.25 | − 13.72 ± 3.97 | < .001† | − 21.56 ± 5.52 | − 15.33 ± 4.18 | .004† | |
|
Light-adapted 3.0 flicker |
Amplitude | .700 | .222 | 52.55 ± 23.92 | 44.22 ± 23.57 | .052† | 56.24 ± 23.98 | 46.79 ± 25.57 | .129† |
| Implicit time | .607 | .326 | 31.69 ± 3.80 | 33.31 ± 3.32 | .010† | 31.07 ± 2.42 | 33.21 ± 4.03 | .021† | |
P values in boldface indicate statistical significance.
*Correlation analysis.
†One-way ANOVA and student t-test for continuous parametric variables.
‡Kruskal–Wallis test and Mann–Whitney U test for continuous nonparametric variables.
¶Visual field improvement was evaluated in only those underwent at least two sequential visual field tests (N = 54).
#Pearson’s Chi-Square Test.
ERG electroretinogram, CRAO central retinal artery occlusion, BCVA best-corrected visual acuity, VFD visual field defect.