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. 2020 Jul 22;10:12146. doi: 10.1038/s41598-020-68957-5

Table 3.

Association of ERG parameters and clinical visual function & prognosis variables in eyes with CRAO.

Parameters Initial BCVA Initial VFDs Visual acuity improvement (N = 110) P†‡ Visual field improvement (N = 54)¶ P†‡
P* P†‡ BCVA improvement (N = 50) No improvement (N = 60) Visual field improvement (N = 25) No improvement (N = 29)
Standard treatment : Intra-arterial thrombolysis 17 : 33 19 : 41 .795# 7 : 18 7 : 22 .805#
Dark-adapted 0.01 B-wave amplitude (μV) .636 .274 131.45 ± 91.55 109.57 ± 92.13 .174 180.81 ± 96.84 139.92 ± 92.96 .120
Implicit time (ms) .597 .661 91.41 ± 17.36 97.52 ± 18.70 .055 87.50 ± 16.47 85.34 ± 15.37 .620
Dark-adapted 3.0 A-wave amplitude .941 .773 163.51 ± 61.19 149.79 ± 67.58 .227 185.79 ± 73.36 170.84 ± 67.30 .438
A-wave implicit time .676 .593 24.41 ± 1.98 24.88 ± 3.35 .310 24.03 ± 2.67 25.07 ± 2.83 .172
B-wave amplitude .339 .093 333.98 ± 67.81 217.19 ± 73.85 .004 342.92 ± 56.48 245.74 ± 65.30 .006
B-wave implicit time .843 .779 50.33 ± 5.55 51.19 ± 7.47 .460 50.28 ± 5.58 50.62 ± 7.44 .850
B/A ratio  < .001  < .001 1.68 ± 0.31 1.43 ± 0.21 .023 1.83 ± 0.23 1.46 ± 0.19 .008

Dark-adapted 3.0

Oscillatory potentials

.691 .641 35.34 ± 21.53 30.01 ± 21.20 .154 44.43 ± 23.77 40.67 ± 21.45 .544

Light-adapted

3.0

A-wave amplitude .250 .289 21.99 ± 11.91 19.33 ± 8.99 .156 10.79 ± 2.15 11.43 ± 2.12 .107
A-wave implicit time .812 .952 16.41 ± 2.48 16.56 ± 3.43 .767 15.71 ± 2.20 14.93 ± 2.60 .244
B-wave amplitude .344 .087 69.34 ± 34.52 63.28 ± 38.41 .330 83.84 ± 37.68 63.96 ± 36.84 .037
B-wave implicit time .597 .084 32.71 ± 2.92 34.17 ± 3.19 .007 32.42 ± 2.28 33.70 ± 3.16 .090
Photopic negative response .071 .375 − 22.14 ± 4.25 − 13.72 ± 3.97  < .001 − 21.56 ± 5.52 − 15.33 ± 4.18 .004

Light-adapted

3.0 flicker

Amplitude .700 .222 52.55 ± 23.92 44.22 ± 23.57 .052 56.24 ± 23.98 46.79 ± 25.57 .129
Implicit time .607 .326 31.69 ± 3.80 33.31 ± 3.32 .010 31.07 ± 2.42 33.21 ± 4.03 .021

P values in boldface indicate statistical significance.

*Correlation analysis.

One-way ANOVA and student t-test for continuous parametric variables.

Kruskal–Wallis test and Mann–Whitney U test for continuous nonparametric variables.

Visual field improvement was evaluated in only those underwent at least two sequential visual field tests (N = 54).

#Pearson’s Chi-Square Test.

ERG electroretinogram, CRAO central retinal artery occlusion, BCVA best-corrected visual acuity, VFD visual field defect.