Table 1.
Baseline characteristics.
Characteristic | BV positive (n = 26) | BV negative (n = 190) | P value | Term (≥ 37 + 0 weeks) (n = 157) | Preterm (≤ 36 + 6 weeks) (n = 39) | P value |
---|---|---|---|---|---|---|
Age | ||||||
Mean (SD)- yrs | 31.0 + /− 4.8 | 31.2 + /− 4.9 | 0.8666 | 31.6 ± 5.0 | 29.8 ± 4.4 | 0.0267* |
Distribution-no. (%) | ||||||
< 35 yrs | 17 (65.4) | 142 (74.7) | 111 (70.7) | 34 (87.2) | ||
≥ 35 yrs | 9 (34.6) | 48 (25.3) | 46 (29.3) | 5 (12.8) | ||
BMI at bookinga | ||||||
Median (IQR)-kg/m2 | 25.0 (22.5–33.0) | 25.3 (22.2–29.4) | 0.5074 | 25.3 (22.4–29.3) | 25.3 (21.8–31.2) | 0.8101 |
Distribution-no. (%) | ||||||
< 30 kg/m2 | 18 (69.2) | 142 (77.6) | 119 (75.8) | 29 (74.4) | ||
≥ 30 kg/m2 | 8 (30.7) | 41 (22.4) | 34 (21.7) | 10 (25.6) | ||
Ethnicityb–no. (%) | ||||||
White | 21 (80.8) | 145 (76.3) | 0.4597 | 124 (79.0) | 33 (84.6) | 0.0608 |
Black | 4 (15.4) | 20 (10.5) | 19 (12.1) | 0 (0) | ||
Asian | 1 (3.8) | 15 (7.9) | 12 (7.6) | 4 (10.3) | ||
Other | 0 | 10 (5.3) | 2 (1.3) | 2 (5.1) | ||
Smoking in pregnancy-no. (%) | ||||||
Yes | 4 (15.4) | 21 (11.1) | 0.8029 | 18 (11.5) | 8 (20.5) | 0.2015 |
No | 20 (76.9) | 152 (80.0) | 127 (80.9) | 30 (76.9) | ||
Not known | 2 (7.7) | 17 (8.9) | 12 (7.6) | 1 (2.6) | ||
Indication for attending clinic-no. (%) | ||||||
Previous preterm ≥ 24 wk to < 34 wk | 50 (31.9) | 30 (76.9) | < 0.0001* | |||
Previous midtrimester loss < 24 wk | 38 (24.2) | 4 (10.3) | ||||
History of cervical surgery | 69 (43.9) | 5 (12.8) | ||||
Gestation at delivery | ||||||
Midtrimester miscarriage | 1 | 1 | – | 2 | ||
Extreme preterm (< 28 weeks) | 2 | 4 | – | 6 | ||
Very preterm (28–31 + 6 weeks) | 3 | 8 | – | 10 | ||
Late preterm (32–36 + 6 weeks) | 7 | 12 | – | 21 | ||
Term (≥ 37 weeks) | 9 | 149 | 157 | – | ||
Not known | 3 | 6 | – | – | ||
Iatrogenic preterm delivery | 1 | 10 | – | – |
This includes 216 patients attending the preterm prevention clinic who had bacterial vaginosis diagnosed in pregnancy versus those who did not, and the 196 patients including who delivered preterm versus term (excluding those who had iatrogenic preterm delivery or if delivery information was not available). Pregnancy outcomes of patients recruited to the study from the preterm prevention clinic are illustrated.
aBMI of 7 women in BV negative group not known and BMI of 4 women in term group not known.
bPatient reported.