Table III.
Tabular representation of the criteria used for obtaining histopathological scores.
Histopathological score | Meaning | Fibrous tissue (H&E and Masson’s Trichrome) | Small vessel numbers (α-SMA) |
---|---|---|---|
0 | WNL | Section consists of white fat and small amounts of dense, sparsely cellular connective tissue | Labelled profiles are widely scattered in entire section |
1 | Minimal | Section contains up to 10% of more cell-dense connective tissue | Labelled profiles have higher density in < 5% of section |
2 | Mild | Section contains about 15% to 30% of more cell-dense connective tissue | Labelled profiles exhibit greater density in 5% to 20% of section |
3 | Moderate | Section contains about 35% to 50% of more cell-dense connective tissue | Labelled profiles exhibit greater density in 25% to 45% of section |
4 | Marked | Section contains about 55% to 80% of more cell-dense connective tissue | Labelled profiles exhibit greater density in 50% to 75% of section |
5 | Severe | Section contains more than 85% cell-dense connective tissue | Labelled profiles exhibit greater density in > 80% of section |
SMA, alpha-smooth muscle actin; H&E, haematoxylin and eosin; WNL, within normal limits.