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Overview of quantitative systems pharmacology Model Structure. Production and degradation reaction for key glycosphingolipids in their appropriate intracellular organelles are included. Glucosylceramide (GL‐1); glucosylsphingosine (lyso‐GL‐1); lactosylceramide (GL‐2); globotriaosylceramide (GL‐3); monosialodihexosylganglioside (GM‐3). PK, pharmacokinetic.
