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. 2020 Jul 23;17:112. doi: 10.1186/s12985-020-01362-6

Fig. 4.

Fig. 4

Classical cap-dependent translation initiation in eukaryotic cells. The process consists of 43S preinitiation complex assembly, 43S preinitiation complex binding to mRNA, initiation codon (AUG) recognition, and 60S ribosomal subunit addition to form a complete initiation complex and start translation [4]