Fig. 1.
RUT prevented DSS-induced acute colitis depending on NRF2. (A and B), body weight change for Nrf2+/+ mice (A) and Nrf2−/− mice (B). (C and D), DAI score for Nrf2+/+ mice (C) and Nrf2−/− mice (D). (E and F), colon length of Nrf2+/+ mice (E) and Nrf2−/− mice (F). *P < 0.05, **P < 0.01*** and P < 0.001, versus vehicle-treated DSS group. Significance was determined by using one-way ANOVA. Data are presented as the mean ± SEM, N = 6 per group.