Table 4. Temporal Trends of ICD-9 and Laboratory Data for Selected Organisms.
| Organism | Performance | % | |||||
|---|---|---|---|---|---|---|---|
| Overall (n = 161 529) | July 2010-June 2011 (n = 37 259) | July 2011-June 2012 (n = 31 302) | July 2012-June 2013 (n = 33 803) | July 2013-June 2014 (n = 32 388) | July 2014-June 2015 (n = 30 148) | ||
| MSSA | ICD-9+ | 0.8 | 0.8 | 0.8 | 0.8 | 0.9 | 0.9 |
| Laboratory+ | 5.4 | 5.8 | 5.4 | 5.4 | 5.3 | 4.8 | |
| Sensitivity | 14.2 | 13.4 | 12.6 | 13.4 | 15.7 | 16.4 | |
| Specificity | 99.9 | 99.9 | 99.9 | 99.9 | 99.9 | 99.9 | |
| PPV | 91.1 | 92.8 | 91.3 | 89.3 | 90.7 | 91.4 | |
| NPV | 95.4 | 94.9 | 95.2 | 95.3 | 95.5 | 95.9 | |
| MRSA | ICD-9+ | 2.3 | 2.4 | 2.4 | 2.4 | 2.4 | 2.1 |
| Laboratory+ | 3.6 | 4.0 | 3.7 | 3.5 | 3.4 | 3.2 | |
| Sensitivity | 49.3 | 47.1 | 48.9 | 50.3 | 50.7 | 49.9 | |
| Specificity | 99.4 | 99.5 | 99.4 | 99.4 | 99.3 | 99.5 | |
| PPV | 76.0 | 80.3 | 75.7 | 75.6 | 72.4 | 75.5 | |
| NPV | 98.1 | 97.8 | 98.1 | 98.2 | 98.3 | 98.4 | |
| Streptococcus pneumoniae | ICD-9+ | 3.0 | 3.2 | 2.8 | 3.3 | 2.9 | 2.6 |
| Laboratory+ | 3.6 | 3.9 | 3.5 | 4.0 | 3.5 | 3.1 | |
| Sensitivity | 60.1 | 61.8 | 60.2 | 61.3 | 58.7 | 56.9 | |
| Specificity | 99.2 | 99.2 | 99.3 | 99.1 | 99.1 | 99.2 | |
| PPV | 73.4 | 75.5 | 74.9 | 74.3 | 70.8 | 70.1 | |
| NPV | 98.5 | 98.5 | 98.6 | 98.4 | 98.5 | 98.6 | |
| Pseudomonas spp | ICD-9+ | 1.6 | 1.8 | 1.7 | 1.6 | 1.4 | 1.3 |
| Laboratory+ | 2.7 | 3.0 | 3.0 | 2.7 | 2.5 | 2.3 | |
| Sensitivity | 46.9 | 49.5 | 44.5 | 48.3 | 45.9 | 45.5 | |
| Specificity | 99.7 | 99.6 | 99.7 | 99.7 | 99.7 | 99.7 | |
| PPV | 80.3 | 81.0 | 79.4 | 79.8 | 80.8 | 80.1 | |
| NPV | 98.5 | 98.5 | 98.3 | 98.6 | 98.6 | 98.7 | |
| Influenza virus | ICD-9+ | 3.7 | 1.9 | 0.9 | 4.1 | 4.7 | 6.9 |
| Laboratory+ | 2.7 | 1.3 | 0.6 | 3.1 | 3.3 | 5.4 | |
| Sensitivity | 95.9 | 91.2 | 92.9 | 96.0 | 96.9 | 96.9 | |
| Specificity | 98.9 | 99.3 | 99.7 | 98.8 | 98.4 | 98.3 | |
| PPV | 70.8 | 61.3 | 63.8 | 72.2 | 67.4 | 76.4 | |
| NPV | 99.9 | 99.9 | 100 | 99.9 | 99.9 | 99.8 | |
Abbreviations: ICD-9, International Classification of Diseases, Ninth Revision; ICD-9+, presence of an ICD-9 code; laboratory+, presence of a laboratory sample identifying an organism; MRSA, methicillin-resistant Staphylococcus aureus; MSSA, methicillin-sensitive Staphylococcus aureus; PPV, positive predictive value; NPV, negative predictive value; spp, several species.