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. 2020 Jul 22;77(12):1235–1245. doi: 10.1001/jamapsychiatry.2020.2148

Table 2. Primary and Secondary Outcome Data Before Therapy vs Postassessment.

Measure Mean (SD) Effect size, Cohen d Mixed linear models, β (SE) Term P value
Pretherapy Postassessment Intent-to-treat populationa P value Population according to protocolb P value
Clinician Administered PTSD Scale
DBT-PTSD 39.93 (10.84) 20.56 (15.81) 1.35 NA 1.66 NA β10 = −4.84 (0.73) Time <.001
CPT 40.96 (8.95) 26.41 (16.04) 0.98 NA 1.25 NA β01 = −0.30 (1.54) Group .85
Comparison NA NA 0.33 .02 0.21 .26 β11 = 0.93 (0.47) Group × time .047
Posttraumatic Stress Disorder Checklist for DSM-5
DBT-PTSD 49.39 (11.46) 23.82 (17.86) 1.55 NA 2.34 NA β10 = −6.98 (0.89) Time <.001
CPT 49.54 (11.04) 33.74 (19.60) 0.90 NA 1.34 NA β01 = −1.24 (1.82) Group .50
Between NA NA 0.57 <.001 0.46 .04 β11 = 1.86 (0.57) Group × time .001
Dissociation Tension Scale–duration
DBT-PTSD 24.13 (16.88) 14.04 (14.58) 0.79 NA 1.23 NA β10 = −3.13 (0.74) Time <.001
CPT 23.96 (14.81) 20.87 (18.08) 0.20 NA 0.31 NA β01 = −0.57 (2.45) Group .82
Comparison NA NA 0.50 <.001 0.30 .20 β11 = 1.17 (0.48) Group × time .02
Dissociation Tension Scale–intensity
DBT-PTSD 2.82 (1.70) 1.77 (1.70) 0.82 NA 1.22 NA β10 = −0.30 (0.08) Time <.001
CPT 3.12 (1.62) 2.61 (1.88) 0.33 NA 0.55 NA β01 = 0.28 (0.27) Group .32
Comparison NA NA 0.39 .007 0.20 0.41 β11 = 0.09 (0.05) Group × time .09
Borderline Symptom List–23
DBT-PTSD 2.01 (0.82) 1.14 (0.86) 1.11 NA 1.4 NA β10 = −0.25 (0.04) Time <.001
CPT 2.04 (0.80) 1.63 (0.95) 0.47 NA 0.72 NA β01 = −0.001 (0.12) Group .99
Comparison NA NA 0.55 <.001 0.27 .22 β11 = 0.08 (0.03) Group × time .003
Borderline Symptom List–behavioral items
DBT-PTSD 0.34 (0.33) 0.18 (0.18) 0.54 NA 0.76 NA NAc NAc NAc
CPT 0.31 (0.28) 0.29 (0.25) 0.08 NA 0.34 NA
Comparison NA NA 0.50 <.001 0.39 .06
Beck Depression Inventory–II
DBT-PTSD 33.24 (11.20) 21.57 (14.04) 0.98 NA 1.37 NA β10 = −3.20 (0.78) Time <.001
CPT 34.10 (10.81) 26.99 (15.09) 0.48 NA 0.76 NA β01 = 0.33 (1.93) Group .86
Comparison NA NA 0.32 .02 0.17 .45 β11 = 0.86 (0.49) Group × time .09
Global Assessment of Functioning
DBT-PTSD 50.75 (9.14) 60.13 (13.95) 0.67 NA 1.12 NA β10 = 2.38 (0.62) Time <.001
CPT 49.19 (7.69) 55.25 (12.55) 0.51 NA 0.87 NA β01 = −0.71 (1.39) Group .61
Comparison NA NA 0.26 .08 0.27 .16 β11 = −0.52 (0.40) Group × time .20

Abbreviations: CPT, cognitive processing therapy; DBT-PTSD, dialectical behavior therapy for posttraumatic stress disorder; NA, not applicable; PTSD, posttraumatic stress disorder.

a

Intent-to-treat: n = 98 (DBT-PTSD), and n = 95 (CPT), respectively; besides the Dissociation Tension Scale–duration under CPT and the Borderline Symptom List–behavioral items under CPT all pre-to-post effect sizes d were statistically different from 0.

b

According to protocol: n = 73 (DBT-PTSD), and n = 58 (CPT), respectively; besides the Dissociation Tension Scale–duration under CPT, all pre-to-post effect sizes d were statistically different from 0.

c

Mixed linear models for the Borderline Symptom List–behavioral items are not reported because the assumption of linearity was not met and the Newton-Raphson algorithms used in generalized linear models did not consistently converge during the procedure of multiple imputation.