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. 2020 Jun 22;183(1):161–175. doi: 10.1007/s10549-020-05752-w

Fig. 1.

Fig. 1

CKMNF116 (a) and aligned Ki67 (b) immunohistochemistry stained tumor slide with automated hot spot detection (pink outline) using APP24. Corresponding heatmap illustrating the areas with highest Ki67% score (c). Tumor cell detection and hot spot region visualized in CKMNF116 (d), Ki67 (e) and heatmap (f). Ki67-positive cells marked in red and Ki67-negative cells in blue