Table 4.

Conditional logistic regression results on the association between clinical variables and the odds of ASDs among boys (n = 274 or 137 pairs).

Variable	Levels	Non-ASD	ASD	OR	95% CI	p value
Cumulative dose of sOT	0 mU	57	51	1
	1st level	37	20	0.61	0.26–1.41	0.250
	2nd level	25	25	1.62	0.63–4.16	0.310
	3rd level	18	41	2.79	1.10–7.06	0.031
Maximum dose rate	0 mU/min	57	51	1
	1st level	29	23	0.85	0.37–1.97	0.709
	2nd level	31	26	1.27	0.55–2.95	0.575
	3rd level	20	37	1.97	0.83–4.69	0.127
Time of exposure	0 min	57	51	1
	1st level	39	17	0.52	0.22–1.22	0.134
	2nd level	23	28	1.79	0.69–4.61	0.229
	3rd level	18	41	3.48	1.29–9.41	0.014

All variables are categorical and coded so that OR > 1 indicates higher odds of ASD. Variables controlled for were maternal hypertension, maternal diabetes, maternal education, indication for delivery (including fetal indications), birth weight, maternal body mass index, mode of delivery, child race, smoking during pregnancy, alcohol use during pregnancy, and paternal age. The exposure variables (cumulative dose of sOT, maximum dose rate, and time of exposure) were run in separate models. Each model consisted of the exposure variable, covariates, and the outcome. ASD: autism spectrum disorder; OR: odds ratio, CI: confidence interval; sOT: synthetic oxytocin.