Table 1.
Demographic characteristics, diseases and median right ventricular strain values of the patients and volunteers
| Patients (n = 57) | Healthy subjects (n = 17) | |
|---|---|---|
| Age (years) | 56 (±19) | 24 (±5) |
| Female, n (%) | 33 (57.9%) | 9 (53%) |
|
LV-dysfunction (LVEF< 50%, e.g. HFrEF, CAD, arrhythmia), n (%) |
17 (29.8%) | / |
|
Preserved LVEF (LVEF> 50%, e.g. HFpEF, CAD, arrhythmia), n (%) |
13 (22.8%) | / |
| Pulmonary hypertension, RV-dysfunction, n (%) | 12 (21%) | / |
| Congenital heart disease, n (%) | 8 (14%) | / |
| Systemic rheumatic/ inflammatory disease, n (%) | 5 (8.8%) | / |
| Symptoms but no diagnosis on cardiac imaging, n (%) | 2 (3.5%) | / |
| Median (IQR) BSA (m2) | 1.9 (1.7–2.0) | 1.8 (1.7–1.9) |
| LVEF (from CMR) (%) | 51.2 (16.1) | 58.6 (5.1) |
| RVEF (from CMR) (%) | 51.8 (14.5) | 53.4 (5.8) |
| LVEF < 50% | 24 (42.1%) | 0 |
| RVEF< 50% | 18 (31.6%) | 2 (11.8%) |
| Median (IQR) GLS for STE | −16.0 (−20.0 to −14.0) | / |
| Median (IQR) FWLS for STE | −21.0 (−26.0 to −17.0) | / |
| Median (IQR) LS for Endo-FT | −25.2 (−32.5 to −21.6) | −27.6 (− 31.7 to −23.2) |
| Median (IQR) LS for Myo-FT | −26.3 (− 30.6 to − 20.6) | −25.6 (− 29.3 to − 22.4) |
| Median (IQR) LS for SENC | −18.0 (− 20.0 to − 15.8) | −18.6 (− 21.0 to − 17.7) |
Abbreviations: BSA Body surface area, LVEF Left ventricular ejection fraction, RVEF Right ventricular ejection fraction, IQR Interquartile range, GLS Global longitudinal strain, FWLS Free wall longitudinal strain, STE Speckle tracking echocardiography, SENC Strain-encoding, FT Feature tracking, Endo-FT Subendocardial strain determined using FT, Myo-FT Midmyocardial strain determined using FT, HFrEF Heart failure and reduced ejection fraction, HFpEF Heart failure and preserved ejection fraction