Table 2.
Kaplan–Meier analysis overall survival for chordoma patients
| Characteristic | 5-year overall survival, % | 10-year overall survival, % | Median overall survival (months) | Kaplan-Meier | |
|---|---|---|---|---|---|
| Log rank χ2 test | p value | ||||
| Age at diagnosis | 164.433 | < 0.001 | |||
| < 40 | 83.8 | 74.4 | – | ||
| 40–60 | 82.8 | 58.7 | 138.0 | ||
| > 60 | 54.3 | 25.2 | 68.0 | ||
| Sex | 2.585 | 0.108 | |||
| Male | 70.5 | 45.9 | 105.0 | ||
| Female | 72.9 | 52.0 | 132.0 | ||
| Marital status | 66.240 | < 0.001 | |||
| Married | 73.7 | 51.5 | 125.0 | ||
| Divorced/separated | 69.5 | 42.8 | 103.0 | ||
| Widowed | 45.2 | 12.5 | 56.0 | ||
| Single | 75.6 | 57.0 | 157.0 | ||
| Primary site | 41.055 | < 0.001 | |||
| Bones of skull and face and associated joints | 79.2 | 65.1 | 253.0 | ||
| Vertebral column | 66.7 | 37.9 | 90.0 | ||
| Pelvic bone, sacrum, coccyx, and associated joints | 66.4 | 40.1 | 91.0 | ||
| Disease stage | 29.554 | < 0.001 | |||
| Localized | 77.6 | 55.3 | 147.0 | ||
| Regional | 71.6 | 48.2 | 105.0 | ||
| Distant | 49.7 | 32.7 | 53.0 | ||
| Unstaged | 65.2 | 39.0 | 89.0 | ||
| Tumor size | 45.181 | < 0.001 | |||
| < 5 cm | 82.3 | 70.9 | 243.0 | ||
| 5–10 cm | 70.5 | 45.9 | 106.0 | ||
| > 10 cm | 55.9 | 32.1 | 70.0 | ||
| Unknown | 67.0 | 41.0 | 94.0 | ||
| Histological type | 12.265 | 0.002 | |||
| Conventional chordoma | 71.5 | 47.6 | 110.0 | ||
| Chondroid chordoma | 76.6 | 72.8 | - | ||
| Dedifferentiated chordoma | 28.6 | 28.6 | 14.0 | ||
| Surgery | 97.790 | < 0.001 | |||
| Surgery not performed | 48.3 | 26.0 | 56.0 | ||
| STR | 78.1 | 58.5 | 154.0 | ||
| GTR | 82.9 | 59.3 | 178.0 | ||
| Unknown extent of resection | 59.1 | 31.9 | 80.0 | ||
| Radiotherapy | 0.140 | 0.708 | |||
| Yes | 72.7 | 47.1 | 106.0 | ||
| No | 70.0 | 49.7 | 120.0 | ||
| Chemotherapy | 11.445 | 0.001 | |||
| Yes | 47.9 | 28.1 | 51.0 | ||
| No | 72.4 | 49.4 | 119.0 | ||
Note: p value < 0.05 are shown in bold
Abbreviations: STR subtotal resection, GTR gross total/radical resection