Table 5.

Univariate and multivariate analysis of overall survival rates based on primary site and disease stage

Characteristic	Univariate analysis		Multivariate analysis
	Hazard ratio (95% CI)	p value	Hazard ratio (95% CI)	p value
Primary site
Bones of skull and face and associated joints		< 0.001		0.017
Married	Reference		Reference
Divorced/separated	2.01 (1.14–3.56)	0.016	2.31 (1.26–4.22)	0.007
Widowed	4.33 (2.35–8.00)	< 0.001	2.34 (1.18–4.65)	0.015
Single	0.74 (0.45–1.21)	0.233	1.15 (0.67–1.95)	0.618
Vertebral column		< 0.001		0.011
Married	Reference		Reference
Divorced/separated	0.81 (0.44–1.51)	0.514	0.94 (0.48–1.86)	0.863
Widowed	3.33 (2.11–5.26)	< 0.001	2.43 (1.44–4.12)	0.001
Single	0.66 (0.39–1.10)	0.111	0.82 (0.48–1.43)	0.488
Pelvic bone, sacrum, coccyx, and associated joints		0.064		0.277
Married	Reference		Reference
Divorced/separated	1.26 (0.72–2.19)	0.423	1.24 (0.69–2.25)	0.477
Widowed	1.74 (1.12–2.71)	0.014	0.96 (0.57–1.60)	0.867
Single	1.36 (0.90–2.05)	0.140	1.54 (0.99–2.38)	0.056
Disease stage
Localized		< 0.001		0.483
Married	Reference		Reference
Divorced/separated	1.15 (0.62–2.17)	0.655	1.17 (0.60–2.29)	0.650
Widowed	3.54 (2.16–5.80)	< 0.001	1.54 (0.89–2.67)	0.126
Single	0.79 (0.48–1.29)	0.340	1.20 (0.70–2.06)	0.519
Regional		< 0.001		0.055
Married	Reference		Reference
Divorced/separated	1.22 (0.77–1.93)	0.401	1.31 (0.81–2.11)	0.266
Widowed	2.80 (1.82–4.32)	< 0.001	1.95 (1.23–3.10)	0.005
Single	0.69 (0.45–1.04)	0.073	1.09 (0.71–1.67)	0.702
Distant		< 0.001		0.159
Married	Reference		Reference
Divorced/separated	6.83 (2.25–20.73)	0.001	4.43 (1.19–16.53)	0.027
Widowed	2.78 (1.14–6.80)	0.025	3.14 (0.71–13.99)	0.133
Single	1.31 (0.69–2.48)	0.405	1.33 (0.58–3.04)	0.497