Table 2.
Parameters | Time points | VehicleA | Ac-YVAD-cmk |
---|---|---|---|
Body weight, g | Baseline | 381 ± 13 | 374 ± 17 |
Time from asphyxia to cardiac arrest, s | Baseline | 220.4 ± 15 | 217.1 ± 23 |
Time required for ROSC, s | Baseline | 99.06 ± 17 | 96.45 ± 22 |
Total dose of epinephrine, μg | Baseline | 12.3 ± 3.1 | 11.1 ± 3.0 |
Mean arterial pressure, mmHg | Baseline | 119 ± 7 | 124 ± 11 |
10 min | 116 ± 12 | 107 ± 7 | |
30 min | 84 ± 9 | 83 ± 5 | |
60 min | 80 ± 5 | 81 ± 11 | |
Heart rate, beats/min | Baseline | 407 ± 11 | 403 ± 7 |
10 min | 431 ± 15 | 427 ± 19 | |
30 min | 372 ± 11 | 369 ± 17 | |
60 min | 383 ± 17 | 379 ± 15 | |
Rectal temperature, °C | Baseline | 36.8 ± 0.4 | 36.9 ± 0.2 |
10 min | 37.1 ± 0.3 | 36.9 ± 0.3 | |
30 min | 37.0 ± 0.2 | 36.8 ± 0.3 | |
60 min | 36.8 ± 0.2 | 36.9 ± 0.2 |
Physiological variables are measured at baseline and at 10, 30, and 60 min after ROSC. The values are expressed as mean ± SD. VehicleA vehicle of Ac-YVAD-cmk