Table 2.

Protection against virulentB. suisinduced by LPS and metabolic mutants inoculated subcutaneously.

Vaccine	Dose (CFU/mouse)	Mean ± SD of log10 CFU in spleen of
		Bs2WT	Vaccine
Bs2ΔwadB	105	3.97 ± 0.37a,b	2.61 ± 0.97
Bs2Δppdk	105	3.65 ± 0.43a,b	2.39 ± 0.54
Bs2ΔppdkΔwadB	105	4.12 ± 1.09a,b	2.68 ± 1.17
Bs2ΔwbkF	108	3.33 ± 0.36a,b	2.45 ± 0.56
Bs2Δwzm	108	2.83 ± 1.88a,b	2.52 ± 1.50
Rev1	105	3.68 ± 0.78a	2.43 ± 0.56
BSS	–	6.69 ± 0.13

Statistical comparison (n = 5) of mean log₁₀ Bs2WT CFU/spleen: ^ap < 0.001 vs. BSS (unvaccinated) and ^bp > 0.05 vs. Rev1.