Table 3.
Comparison of clinical outcomes of IVF-ET cycles among the four groups
| Control | 1, 9, 16qh+/− group | D/G group | inv(9) | |
|---|---|---|---|---|
| No. of case | 908 | 90 | 33 | 44 |
| No. oocytes retrieved | 13.67 ± 5.87 | 12.41 ± 6.93 | 13.88 ± 7.83 | 13.59 ± 8.39 |
| 1PN fertilization rate (%) | 3.45 ± 6.01 | 4.40 ± 1.25 | 2.07 ± 3.99 | 1.71 ± 7.71 |
| 2PN fertilization rate (%) | 56.39 ± 19.46 | 57.19 ± 23.44 | 57.41 ± 23.92 | 57.49 ± 27.33 |
| Multi-PN fertilization rate (%) | 9.73 ± 10.75 | 9.07 ± 10.78 | 10.28 ± 16.01 | 5.49 ± 8.09 |
| Fertilization rate (%) | 69.58 ± 19.44 | 70.44 ± 21.03 | 67.59 ± 25.52 | 64.70 ± 26.80 |
| 2PN cleavage rate (%) | 97.66 ± 7.15 | 96.36 ± 16.07 | 92.59 ± 23.84a | 88.58 ± 29.17a |
| Quality embryo rate (%) | 54.48 ± 24.92 | 53.04 ± 27.99 | 53.74 ± 26.23 | 55.69 ± 32.93 |
| Implantation rate (%) | 32.4 (394/1215) | 30.4 (38/125) | 30.8 (12/39) | 37.5 (18/48) |
| Clinical pregnancy rate (%) | 47.3 (298/630) | 47.0 (31/66) | 45 (9/20) | 58.3 (14/24) |
| Early miscarriage rate (%) | 3.0 (9/298) | 3.2 (1/31)* | 0 (0/9) | 21.4 (3/14)b* |
aP < 0.05, difference between chromosomal polymorphisms group and the control group
bP < 0.01, difference between chromosomal polymorphisms group and the control group
PN pronuclei
*Fisher’s exact test
All continuous variables are expressed as mean ± SD