Table 4.
Comparison of the outcomes of ICSI-ET cycles among the four groups
| Control | 1, 9, 16qh+/− group | D/G group | inv(9) | |
|---|---|---|---|---|
| No. of case | 180 | 39 | 22 | 18 |
| No. oocytes retrieved | 12.93 ± 5.61 | 14.31 ± 6.69 | 15.91 ± 6.54 | 13.56 ± 8.34 |
| 1PN fertilization rate | 2.49 ± 4.82 | 3.37 ± 6.81 | 1.76 ± 3.72 | 5.53 ± 6.32 |
| 2PN fertilization rate | 54.03 ± 20.84 | 55.45 ± 19.63 | 53.93 ± 20.07 | 56.13 ± 23.97 |
| Multi-PN fertilization rate | 1.87 ± 4.84 | 1.92 ± 3.64 | 1.45 ± 3.44 | 1.34 ± 3.63 |
| Fertilization rate (%) | 59.07 ± 19.02 | 60.74 ± 19.53 | 57.13 ± 19.24 | 63.00 ± 22.82 |
| 2PN cleavage rate (%) | 97.16 ± 11.52 | 95.11 ± 17.93 | 98.46 ± 4.24 | 93.03 ± 23.45 |
| Quality embryo rate (%) | 52.33 ± 28.15 | 57.18 ± 32.22 | 59.27 ± 18.34 | 50.46 ± 28.69 |
| Implantation rate (%) | 23.69 (59/190) | 28.6 (16/56) | 44.8 (13/29)a | 30.8 (8/26) |
| Clinical pregnancy rate (%) | 40.65 (50/123) | 37.9 (11/29) | 78.6 (11/14)a | 61.5 (8/13) |
| Early miscarriage rate (%) | 2 (1/50)* | 9.1 (1/11)* | 0 (0/11) | 50 (4/8)b* |
aP value < 0.05, difference between chromosomal polymorphisms group and control group
bP value < 0.01, difference between chromosomal polymorphisms group and control group
PN pronuclei
*Fisher’s exact test
All continuous variables are expressed as mean ± SD