Table 5.
Comparison of the IVF/ICSI outcomes among the four groups
| Control | 1, 9, 16qh+/− group | D/G group | inv(9) group | ||||
|---|---|---|---|---|---|---|---|
| Female | Male | Female | Male | Female | Male | ||
| No. of case | 1088 | 54 | 75 | 24 | 31 | 37 | 25 |
| No. oocytes retrieved | 13.55 ± 5.83 | 12.27 ± 6.77 | 13.51 ± 6.98 | 15.08 ± 7.92 | 14.37 ± 7.01 | 13.73 ± 7.65 | 13.36 ± 9.36 |
| 1PN fertilization rate (%) | 3.29 ± 5.84 | 3.53 ± 6.28 | 4.50 ± 13.70 | 2.04 ± 3.71 | 1.88 ± 4.03 | 4.35 ± 9.30 | 0.56 ± 1.94ab |
| 2PN fertilization rate (%) | 56.00 ± 19.71 | 57.09 ± 21.28 | 56.34 ± 23.16 | 49.72 ± 24.8b | 60.7 ± 19.38 | 53.51 ± 28.19 | 62.39 ± 22.47 |
| Multi-PN fertilization rate (%) | 8.43 ± 10.04 | 7.07 ± 11.27 | 6.79 ± 8.59 | 3.25 ± 10.31ab | 9.49 ± 14.78 | 3.51 ± 6.60a | 5.45 ± 8.24 |
| Fertilization rate (%) | 67.73 ± 20.08 | 67.34 ± 20.74 | 67.63 ± 21.32 | 55.01 ± 27.43ab | 69.84 ± 18.32 | 61.37 ± 27.89a | 68.40 ± 21.42 |
| 2PN cleavage rate (%) | 97.58 ± 8.03 | 96.54 ± 15.15 | 95.57 ± 17.68 | 90.67 ± 28.16ab | 98.06 ± 4.42 | 86.44 ± 31.40ab | 94.95 ± 19.99 |
| Quality embryo rate (%) | 54.02 ± 25.63 | 53.05 ± 29.745 | 55.22 ± 29.09 | 55.68 ± 23.66 | 56.09 ± 23.63 | 54.88 ± 34.46 | 53.13 ± 22.52 |
| Implantation rate (%) | 32.24 (453/1405) | 33.75 (27/80) | 26.73 (27/101) | 34.38 (11/32) | 38.89 (14/36) | 31.91 (15/47) | 40.74 (11/27) |
| Clinical pregnancy rate (%) | 46.22 (348/753) | 53.66 (22/41) | 37.04 (20/54) | 56.25 (9/16) | 61.11 (11/18) | 56.52 (13/23) | 64.29 (9/14) |
| Early miscarriage rate (%) | 2.87 (10/348) | 0 | 10 (2/20)* | 0 | 0 | 23.08 (3/13)a* | 44.44 (4/9)* |
aP value < 0.05, difference between chromosomal polymorphisms group and control group
bP value < 0.05, difference between female carriers and male carriers
PN pronuclei
*Fisher’s exact test
All continuous variables are expressed as mean ± SD