Figure 1.

Long-chain non-coding RNA metastasis-related lung adenocarcinoma transcript 1 (lncRNA MALAT1) is highly expressed in the plasma and hypoxic human pulmonary artery smooth muscle cells (hPASMCs) of patients with PAH. (A) Quantitative reverse transcription-PCR (qRT-PCR) detection of plasma lncRNA MALAT1 levels. (B) Receiver operating curve (ROC) for the diagnosis of PAH based on plasma lncRNA MALAT1 level. (C) Comparison of lncRNA MALAT1 levels in hypoxic and non-hypoxic hPASMC cells by RT-qPCR