Table I.

Association between RNF2 protein and mRNA expression and the clinicopathological characteristics of patients with SCC.

Characteristic	n	RNF2 protein positive rate	χ2	P-value	RNF2 mRNA positive rate	χ2	P-value
Sex
Male	140	119 (85.00)	0.155	0.586	115 (82.14)	0.022	0.878
Female	108	91 (84.26)			86 (79.63)
Age (years)
<40	49	41 (83.67)	0.192	0.675	39 (79.59)	0.039	0.943
≥40	199	169 (84.92)			162 (81.41)
Tumor diameter (cm)
<5	104	80 (76.92)	0.145	0.010	75 (72.12)	0.113	0.021
≥5	144	130 (90.28)			126 (87.50)
Degree of tumor differentiation
High and moderate differentiation	58	28 (48.28)	0.499	0.002	27 (46.55)	0.441	0.003
Poor differentiation	190	182 (95.79)			174 (91.58)
Tumor stage
I–II	68	41 (60.29)	7.131	0.004	37 (54.41)	6.928	0.005
III–IV	180	169 (93.89)			164 (91.11)
Lymph node metastasis
Yes	86	81 (94.19)	0.219	0.032	79 (91.86)	0.201	0.031
No	162	129 (79.63)			122 (75.31)
Tumor site
Head	119	103 (86.55)	0.209	0.912	99 (83.19)	0.129	0.372
Face	77	64 (83.12)			61 (79.22)
Neck	52	43 (82.69)			41 (78.85)

RNF2, ring finger protein 2; SCC, skin squamous cell carcinoma.