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miR-147 directly targets BDNF. (A) The binding sites between miR-147 and BDNF. (B) Luciferase reporter assay. (C) miR-147 mimics or inhibitor regulated BDNF expression in A549 cells. (D) BDNF expression in NSCLC tissues and normal tissues. (E) The negative correlation between miR-147 and BDNF expression in NSCLC tissues, **P<0.01. BDNF, brain-derived neurotrophic factor; NSCLC, non-small cell lung cancer.
