Table 3. Comparison of Different Methods for 8-Oxo-dG Analysisa.
detection method | LOD | detection range | detection time |
---|---|---|---|
Rayleigh light scattering*39 | 27.3 pM | 90.8 pM–14.1 nM | 25 min |
resonance light scattering43 | 11 pM | 32 pM–12 nM | 45 min |
fluorescence*44 | 1.19 nM | 3.96–211 nM | 65 min |
fluorescence45 | 4 pM | 0.02–70 nM | 9 h 25 min |
chiroplasmonic*42 | 33 pM | 0.05–2 nM | 60 min |
high-performance liquid chromatography-mass spectrometry (HPLC-MS)*46 | 0.35 aM | 0.18 fM–0.706 pM | 11 min |
electrochemical*30 | 2.5 pM | 10 pM–100 μM | 2 h 40 min |
electrochemical47 | 36.67 nM | 0.05–536.5 μM | |
electrochemiluminescence48 | 25 fM | 100 fM–10 nM | |
fluorometric and colorimetric*49 | ∼350 pM | 0.5–500 nM | 30 min |
colorimetric*50 | 141 pM | 466 pM–247 nM | 1.50 h |
colorimetric*51 | 1.7 nM | 5.6–282 nM | 25 min |
present work (66-nt aptasensor with a portable device) | 9.8 nM | 15–100 nM | 30 min |
The detection methods using the same aptamer as the present work (66-nt aptamer) are denoted with asterisks (*).