Table I.
Association between PD-L1 expression levels and clinicopathological variables of patients with colorectal cancer.
| Variable | PD-L1 (+), n (%) | PD-L1 (−), n (%) | χ2-value | P-value |
|---|---|---|---|---|
| Age, years | ||||
| >65 | 13 (41.9) | 59 (39.3) | 0.073 | 0.788 |
| ≤65 | 18 (58.1) | 91 (60.7) | ||
| Sex | ||||
| Male | 13 (41.9) | 86 (57.3) | 2.458 | 0.117 |
| Female | 18 (58.1) | 64 (42.7) | ||
| Tumor size | ||||
| >5 cm | 10 (32.3) | 92 (61.3) | 8.830 | 0.003 |
| ≤5 cm | 21 (67.7) | 58 (38.7) | ||
| Tumor classification | ||||
| Tubular adenocarcinoma | 22 (71.0) | 121 (80.7) | 4.002 | 0.135 |
| Mucinous adenocarcinoma | 5 (16.1) | 23 (15.3) | ||
| Other | 4 (12.9) | 6 (4.0) | ||
| Vascular and lymphatic infiltration | ||||
| No | 11 (35.5) | 95 (63.3) | 8.221 | 0.004 |
| Yes | 20 (64.5) | 55 (36.7) | ||
| Perineurium invasion | ||||
| No | 21 (67.7) | 119 (79.3) | 1.970 | 0.160 |
| Yes | 10 (32.3) | 31 (20.7) | ||
| Tumor location | ||||
| Rectum | 12 (38.7) | 74 (49.3) | 1.163 | 0.281 |
| Colon | 19 (61.3) | 76 (50.7) | ||
| Tumor differentiation | ||||
| Medium and high differentiation | 13 (41.9) | 134 (89.3) | 37.831 | <0.001 |
| Poorly differentiated | 18 (58.1) | 16 (10.7) | ||
| Tumor-node-metastasis stage | ||||
| I–II | 11 (35.5) | 85 (56.7) | 4.628 | 0.031 |
| III | 20 (64.5) | 65 (43.3) |
PD-L1, programmed death ligand 1.