Table II.
Associations between clinicopathological characteristics and intensity of immunohistochemical survivin expression.
| Survivin staining pattern-intensity (%) | |||
|---|---|---|---|
| Clinicopathological parameters | Moderate, n (%) | Strong, n (%) | P-value |
| Age, years | |||
| <60 | 16 (36.4) | 7 (16.3) | 0.051 |
| ≥60 | 28 (63.6) | 36 (83.7) | |
| Histological type | |||
| Endometrioid | 42 (95.5) | 35 (81.4) | 0.049 |
| Clear cell and papillary serous | 2 (4.5) | 8 (18.6) | |
| Clinical stage | |||
| I | 36 (92.3) | 25 (67.6) | 0.012 |
| II | 3 (7.7) | 9 (24.3) | |
| III | 0 (0.0) | 3 (8.1) | |
| IV | 0 (0.0) | 0 (0.0) | |
| Histological differentiation | |||
| G1 | 14 (31.8) | 4 (9.3) | 0.001 |
| G2 | 25 (56.8) | 20 (46.5) | |
| G3 | 5 (11.4) | 19 (44.2) | |
| Myometrial invasion | |||
| <1/2 | 21 (47.7) | 7 (16.3) | 0.003 |
| ≥1/2 | 23 (52.3) | 36 (83.7) | |
| Lymph-vascular space invasion | |||
| Positive | 0 (0.0) | 11 (33.3) | 0.002 |
| Negative | 23 (100.0) | 22 (66.7) | |
| Fallopian tube and/or ovarian invasion | |||
| Positive | 3 (18.7) | 12 (48.0) | 0.097 |
| Negative | 13 (81.3) | 13 (52.0) | |
| Tumoral necrosis | |||
| Yes | 1 (4.3) | 6 (21.4) | 0.112 |
| No | 22 (95.7) | 22 (78.6) | |