Table IV.
Co-expression of survivin and PTEN in endometrial carcinoma according to scores of immunopositive cells in relation to clinopathological parameters.
| Characteristics | Patients with survivin and PTEN low scores positive expression, n (%) | Patients with either survivin or PTEN moderate scores positive expression, n (%) | P-value |
|---|---|---|---|
| Age, years | |||
| <60 | 4 (57.1) | 17 (25.4) | 0.095 |
| ≥60 | 3 (42.9) | 50 (74.6) | |
| Histological type | |||
| Endometrioid | 6 (85.7) | 58 (86.6) | >0.999 |
| Clear cell and papillary serous | 1 (14.3) | 9 (13.4) | |
| Clinical stage | |||
| I | 7 (100.0) | 46 (79.3) | 0.444 |
| II | 0 (0.0) | 9 (15.5) | |
| III | 0 (0.0) | 3 (5.2) | |
| Histological differentiation | |||
| G1 | 0 (0.0) | 13 (19.4) | 0.143 |
| G2 | 6 (85.7) | 32 (47.8) | |
| G3 | 1 (14.3) | 22 (32.8) | |
| Myometrial invasion | |||
| <1/2 | 1 (14.3) | 22 (32.8) | 0.424 |
| ≥1/2 | 6 (85.7) | 45 (67.2) | |
| Lymph-vascular space invasion | |||
| Yes | 3 (50.0) | 8 (18.6) | 0.117 |
| No | 3 (50.0) | 35 (81.4) | |
| Fallopian tube and/or ovarian invasion | |||
| Yes | 0 (0.0) | 11 (35.5) | 0.285 |
| No | 4 (100.0) | 20 (64.5) | |
| Tumoral necrosis | |||
| Yes | 1 (20.0) | 4 (10.5) | >0.999 |
| No | 4 (80.0) | 34 (89.5) |
PTEN, phosphatase and tensin homolog.