Table V.

Co-expression of survivin and PTEN in endometrial carcinomas according to stain intensity of immunopositive cells in relation to clinopathological parameters.

Characteristics	Patients with survivin and PTEN weak positive expression, n (%)	Patients with either survivin or PTEN moderate positive expression, n (%)	Patients with survivin and PTEN strong positive expression, n (%)	P-value
Age, years
<60	1 (9.1)	15 (32.6)	1 (33.3)	0.145
≥60	10 (90.9)	31 (67.4)	2 (66.7)
Histological type
Endometrioid	9 (81.8)	44 (95.7)	2 (66.7)	0.098
Clear cell and papillary serous	2 (18.2)	2 (4.3)	1 (33.3)
Clinical stage
I	8 (88.9)	34 (82.9)	3 (100.0)	0.366
II	1 (11.1)	4 (9.8)	0 (0.0)
III	0 (0.0)	3 (7.3)	0 (0.0)
Histological differentiation
G1	6 (54.5)	11 (23.9)	0 (0.0)	0.023
G2	3 (27.3)	24 (52.2)	2 (66.7)
G3	2 (18.2)	11 (23.9)	1 (33.3)
Myometrial invasion
<1/2	5 (45.5)	17 (37.0)	0 (0.0)	0.479
≥1/2	6 (54.5)	29 (63.0)	3 (100.0)
Lymph-vascular space invasion
Yes	0 (0.0)	4 (14.3)	2 (100.0)	0.007
No	9 (100.0)	24 (85.7)	0 (0.0)
Fallopian tube and/or ovarian invasion
Yes	1 (16.7)	6 (28.6)	0 (0.0)	0.031
No	5 (83.3)	15 (71.4)	0 (0.0)
Tumoral necrosis
Yes	0 (0.0)	4 (15.4)	0 (0.0)	0.516
No	9 (100.0)	22 (84.6)	0 (0.0)

P<0.05, statistically significant results; 0.05<P<0.10, suggestive results. PTEN, phosphatase and tensin homolog.