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. 2020 May 30;20(2):1033–1054. doi: 10.3892/ol.2020.11690

Table VI.

Co-expression of survivin and PTEN in endometrial carcinomas according to sum of stain intensity and scores of immunopositive cells in relation to clinopathological parameters.

Characteristics Patients with either survivin or PTEN ++ expression, n (%) Patients with survivin and PTEN +++ expression, n (%) P-value
Age, years
  <60 17 (29.8) 1 (50.0) 0.101
  ≥60 40 (70.2) 1 (50.0)
Histological type
  Endometrioid   54 (94.7) 1 (50.0) 0.020
  Clear cell and papillary serous 3 (5.3) 1 (50.0)
Clinical stage
  I 40 (80.0) 2 (100.0) 0.837
  II 7 (14.0) 0 (0.0)
  III 3 (6.0) 0 (0.0)
Histological differentiation
  G1 12 (21.1) 0 (0.0) 0.363
  G2 32 (56.1) 1 (50.0)
  G3 13 (22.8) 1 (50.0)
Myometrial invasion
  <1/2 18 (31.6) 0 (0.0) 0.425
  ≥1/2 39 (68.4) 2 (100.0)
Lymph-vascular space invasion
  Yes 8 (21.6) 1 (50.0) 0.272
  No 29 (78.4) 1 (50.0)
Fallopian tube and/or ovarian invasion
  Yes 10 (34.5) 0 (0.0) 0.352
  No 19 (65.5) 0 (0.0)
Tumoral necrosis
  Yes 5 (14.7) 0 (0.0) 0.687
  No 29 (85.3) 0 (0.0)

P<0.05, statistically significant results; 0.05<P<0.10, suggestive results. PTEN, phosphatase and tensin homolog.