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. 2020 May 22;20(2):1213–1220. doi: 10.3892/ol.2020.11667

Figure 4.

Figure 4.

Effects of miR-518b on NSCLC cell proliferation, migration and invasion in A549 and PC9 cell lines. (A) miR-518b expression in A549 and PC9 cells was upregulated following transfection with miR-518b mimic and downregulated following transfection with miR-518b inhibitor. (B) NSCLC cell proliferation in A549 and PC9 cells was facilitated by overexpression of miR-518b and inhibited following knockdown of miR-518b. Overexpression of miR-518b enhanced (C) cell migration and (D) invasion in A549 and PC9 cells, while miR-518b knockdown reversed these effects. Magnification, ×200; *P<0.05, **P<0.01, ***P<0.001, compared to mock. miR, microRNA; NSCLC, non-small cell lung cancer; NC, negative control.